Cargando…

A Novel 5-Chloro-N-phenyl-1H-indole-2-carboxamide Derivative as Brain-Type Glycogen Phosphorylase Inhibitor: Potential Therapeutic Effect on Cerebral Ischemia

Brain-type glycogen phosphorylase inhibitors are potential new drugs for treating ischemic brain injury. In our previous study, we reported compound 1 as a novel brain-type glycogen phosphorylase inhibitor with cardioprotective properties. We also found that compound 1 has high blood–brain barrier p...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Yatao, Li, Shuai, Wang, Youde, Yan, Zhiwei, Guo, Yachun, Zhang, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572471/
https://www.ncbi.nlm.nih.gov/pubmed/36234871
http://dx.doi.org/10.3390/molecules27196333