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Synthesis of Novel Lipophilic Polyamines via Ugi Reaction and Evaluation of Their Anticancer Activity

Natural polyamines (PAs) are involved in the processes of proliferation and differentiation of cancer cells. Lipophilic synthetic polyamines (LPAs) induce the cell death of various cancer cell lines. In the current paper, we have demonstrated a new method for synthesis of LPAs via the multicomponent...

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Detalles Bibliográficos
Autores principales: Nichugovskiy, Artemiy, Maksimova, Varvara, Trapeznikova, Ekaterina, Eshtukova-Shcheglova, Elizaveta, Ivanov, Igor, Yakubovskaya, Marianna, Kirsanov, Kirill, Cheshkov, Dmitry, Tron, Gian Cesare, Maslov, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572921/
https://www.ncbi.nlm.nih.gov/pubmed/36234753
http://dx.doi.org/10.3390/molecules27196218