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Inhibition of major histocompatibility complex-I antigen presentation by sarbecovirus ORF7a proteins
Viruses employ a variety of strategies to escape or counteract immune responses, including depletion of cell surface major histocompatibility complex class I (MHC-I), that would ordinarily present viral peptides to CD8(+) cytotoxic T cells. As part of a screen to elucidate biological activities asso...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573092/ https://www.ncbi.nlm.nih.gov/pubmed/36136978 http://dx.doi.org/10.1073/pnas.2209042119 |