Inhibition of major histocompatibility complex-I antigen presentation by sarbecovirus ORF7a proteins

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Viruses employ a variety of strategies to escape or counteract immune responses, including depletion of cell surface major histocompatibility complex class I (MHC-I), that would ordinarily present viral peptides to CD8(+) cytotoxic T cells. As part of a screen to elucidate biological activities asso...

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Detalles Bibliográficos
Autores principales: Zhang, Fengwen, Zang, Trinity M., Stevenson, Eva M., Lei, Xiao, Copertino, Dennis C., Mota, Talia M., Boucau, Julie, Garcia-Beltran, Wilfredo F., Jones, R. Brad, Bieniasz, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573092/
https://www.ncbi.nlm.nih.gov/pubmed/36136978
http://dx.doi.org/10.1073/pnas.2209042119

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