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Design, Synthesis, and Bioactivity Study of Novel Tryptophan Derivatives Containing Azepine and Acylhydrazone Moieties

Based on the scaffolds widely used in drug design, a series of novel tryptophan derivatives containing azepine and acylhydrazone moieties have been designed, synthesized, characterized, and evaluated for their biological activities. The bioassay results showed that the target compounds possessed mod...

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Detalles Bibliográficos
Autores principales: Zhang, Jingjing, Yang, Rongxin, Li, Lili, Liu, Jianhua, Liu, Yuxiu, Song, Hongjian, Wang, Qingmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573203/
https://www.ncbi.nlm.nih.gov/pubmed/36235237
http://dx.doi.org/10.3390/molecules27196700