Folic Acid Antimetabolites (Antifolates): A Brief Review on Synthetic Strategies and Application Opportunities

Antimetabolites of folic acid represent a large group of drugs and drug candidates, including those for cancer chemotherapy. In this current review, the most common methods and approaches are presented for the synthesis of therapeutically significant antimetabolites of folic acid, which are Methotre...

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Detalles Bibliográficos
Autores principales: Kovalev, Igor S., Zyryanov, Grigory V., Santra, Sougata, Majee, Adinath, Varaksin, Mikhail V., Charushin, Valery N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573478/
https://www.ncbi.nlm.nih.gov/pubmed/36234766
http://dx.doi.org/10.3390/molecules27196229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573478/
https://www.ncbi.nlm.nih.gov/pubmed/36234766
http://dx.doi.org/10.3390/molecules27196229

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