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Folic Acid Antimetabolites (Antifolates): A Brief Review on Synthetic Strategies and Application Opportunities
Antimetabolites of folic acid represent a large group of drugs and drug candidates, including those for cancer chemotherapy. In this current review, the most common methods and approaches are presented for the synthesis of therapeutically significant antimetabolites of folic acid, which are Methotre...
Autores principales: | Kovalev, Igor S., Zyryanov, Grigory V., Santra, Sougata, Majee, Adinath, Varaksin, Mikhail V., Charushin, Valery N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573478/ https://www.ncbi.nlm.nih.gov/pubmed/36234766 http://dx.doi.org/10.3390/molecules27196229 |
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