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Structural Variations in the Central Heterocyclic Scaffold of Tripartite 2,6-Difluorobenzamides: Influence on Their Antibacterial Activity against MDR Staphylococcus aureus

Five series of heterocyclic tripartite 2,6-difluorobenzamides, namely 1,2,3-triazoles, 1,2,4- and 1,3,4-oxadiazoles, analogs of reported model anti-staphylococcal compounds, were prepared. The purpose was to investigate the influence of the nature of the heterocyclic central scaffold on the biologic...

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Detalles Bibliográficos
Autores principales: Barbier, Thibaut, Badiou, Cédric, Davy, Floriane, Queneau, Yves, Dumitrescu, Oana, Lina, Gérard, Soulère, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573484/
https://www.ncbi.nlm.nih.gov/pubmed/36235156
http://dx.doi.org/10.3390/molecules27196619