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Inhibition of MORC2 Mediates HDAC4 to Promote Cellular Senescence through p53/p21 Signaling Axis

(1) Background: Colorectal cancer (CRC) is a common gastrointestinal malignancy, accounting for the second largest gastrointestinal tumor. MORC2, a newly discovered chromatin remodeling protein, plays an important role in the biological processes of various cancers. However, the potential mechanisti...

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Detalles Bibliográficos
Autores principales: Ou, Kepeng, Li, Youjian, Long, Yiling, Luo, Yafei, Tang, Dianyong, Chen, Zhongzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573567/
https://www.ncbi.nlm.nih.gov/pubmed/36234785
http://dx.doi.org/10.3390/molecules27196247