Deactivatable Bisubstrate Inhibitors of Protein Kinases

Bivalent ligands, including bisubstrate inhibitors, are conjugates of pharmacophores, which simultaneously target two binding sites of the biomolecule. Such structures offer attainable means for the development of compounds whose ability to bind to the biological target could be modulated by an exte...

Descripción completa

Detalles Bibliográficos
Autores principales: Sõrmus, Tanel, Lavogina, Darja, Enkvist, Erki, Uri, Asko, Viht, Kaido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573699/
https://www.ncbi.nlm.nih.gov/pubmed/36235226
http://dx.doi.org/10.3390/molecules27196689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573699/
https://www.ncbi.nlm.nih.gov/pubmed/36235226
http://dx.doi.org/10.3390/molecules27196689

Ejemplares similares