Ex vivo engineered human plasma cells exhibit robust protein secretion and long-term engraftment in vivo

Due to their unique longevity and capacity to secrete high levels of protein, plasma B cells have the potential to be used as a cell therapy for protein replacement. Here, we show that ex vivo engineered human plasma cells exhibit single-cell RNA profiles, scanning electron micrograph ultrastructura...

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Detalles Bibliográficos
Autores principales: Cheng, Rene Yu-Hong, Hung, King L., Zhang, Tingting, Stoffers, Claire M., Ott, Andee R., Suchland, Emmaline R., Camp, Nathan D., Khan, Iram F., Singh, Swati, Yang, Ying-Jen, Rawlings, David J., James, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573882/
https://www.ncbi.nlm.nih.gov/pubmed/36245034
http://dx.doi.org/10.1038/s41467-022-33787-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573882/
https://www.ncbi.nlm.nih.gov/pubmed/36245034
http://dx.doi.org/10.1038/s41467-022-33787-8

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