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Wnt/β-catenin signaling pathway is activated in the progress of mandibular condylar cartilage degeneration and subchondral bone loss induced by overloaded functional orthopedic force (OFOF)
OBJECTIVE: To explore the role of Wnt/β-catenin signaling pathway in the pathogenesis and progression of temporomandibular joint osteoarthritis (TMJ OA) caused by overloaded force. MATERIALS AND METHODS: We generated a rat model of forward mandibular extension device to induce TMJ OA by overloaded f...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573886/ https://www.ncbi.nlm.nih.gov/pubmed/36262297 http://dx.doi.org/10.1016/j.heliyon.2022.e10847 |