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Wnt/β-catenin signaling pathway is activated in the progress of mandibular condylar cartilage degeneration and subchondral bone loss induced by overloaded functional orthopedic force (OFOF)

OBJECTIVE: To explore the role of Wnt/β-catenin signaling pathway in the pathogenesis and progression of temporomandibular joint osteoarthritis (TMJ OA) caused by overloaded force. MATERIALS AND METHODS: We generated a rat model of forward mandibular extension device to induce TMJ OA by overloaded f...

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Detalles Bibliográficos
Autores principales: He, Zijing, Liu, Meixi, Zhang, Qiang, Tian, Yihong, Wang, Lingzhi, Yan, Xiao, Ren, Dapeng, Yuan, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573886/
https://www.ncbi.nlm.nih.gov/pubmed/36262297
http://dx.doi.org/10.1016/j.heliyon.2022.e10847