Early growth response-1 is a new substrate of the GSK3β-FBXW7 axis

EGR1, a short-lived transcription factor, regulates several biological processes, including cell proliferation and tumor progression. Whether and how EGR1 is regulated by Cullin-RING ligases (CRLs) remains elusive. Here, we report that MLN4924, a small molecule inhibitor of neddylation, causes EGR1...

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Detalles Bibliográficos
Autores principales: Yin, Lu, Zhang, Jiagui, Sun, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573921/
https://www.ncbi.nlm.nih.gov/pubmed/36240645
http://dx.doi.org/10.1016/j.neo.2022.100839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573921/
https://www.ncbi.nlm.nih.gov/pubmed/36240645
http://dx.doi.org/10.1016/j.neo.2022.100839

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