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The role of immune checkpoints in cardiovascular disease

Immune checkpoint inhibitors (ICI) are monoclonal antibodies which bind to immune checkpoints (IC) and their ligands to prevent inhibition of T-cell activation by tumor cells. Currently, multiple ICI are approved targeting Cytotoxic T-lymphocyte antigen 4 (CTLA-4), Programmed Death Protein 1 (PD-1)...

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Detalles Bibliográficos
Autores principales: Yousif, Laura I., Tanja, Anniek A., de Boer, Rudolf A., Teske, Arco J., Meijers, Wouter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574006/
https://www.ncbi.nlm.nih.gov/pubmed/36263134
http://dx.doi.org/10.3389/fphar.2022.989431