A-Kinase Anchor Protein 1 deficiency causes mitochondrial dysfunction in mouse model of hyperoxia induced acute lung injury

Background: Critically ill patients on supplemental oxygen therapy eventually develop acute lung injury (ALI). Reactive oxygen species (ROS) produced during ALI perturbs the mitochondrial dynamics resulting in cellular damage. Genetic deletion of the mitochondrial A-kinase anchoring protein 1 (Akap1...

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Detalles Bibliográficos
Autores principales: Soundararajan, Ramani, Hernández-Cuervo, Helena, Stearns, Timothy M, Griswold, Anthony J, Patil, Sahebgowda Sidramagowda, Fukumoto, Jutaro, Narala, Venkata Ramireddy, Galam, Lakshmi, Lockey, Richard, Kolliputi, Narasaiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574061/
https://www.ncbi.nlm.nih.gov/pubmed/36263130
http://dx.doi.org/10.3389/fphar.2022.980723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574061/
https://www.ncbi.nlm.nih.gov/pubmed/36263130
http://dx.doi.org/10.3389/fphar.2022.980723

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