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The impact of circadian rhythms on the immune response to influenza vaccination in middle-aged and older adults (IMPROVE): a randomised controlled trial

BACKGROUND: Vaccination is important in influenza prevention but the immune response wanes with age. The circadian nature of the immune system suggests that adjusting the time of vaccination may provide an opportunity to improve immunogenicity. Our previous cluster trial in Birmingham suggested diff...

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Detalles Bibliográficos
Autores principales: Liu, Yihao, Zhang, Hui, Yuan, Gang, Yao, Mi, Li, Bin, Chen, Jianying, Fan, Yuling, Mo, Ruohui, Lai, Fenghua, Chen, Xinwen, Li, Mengyuan, Chen, Binfeng, Lord, Janet M., Peng, Sui, Cheng, KarKeung, Xiao, Haipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574181/
https://www.ncbi.nlm.nih.gov/pubmed/36253778
http://dx.doi.org/10.1186/s12979-022-00304-w