Vaccine models predict rules for updating vaccines against evolving pathogens such as SARS-CoV-2 and influenza in the context of pre-existing immunity

Currently, vaccines for SARS-CoV-2 and influenza viruses are updated if the new vaccine induces higher antibody-titers to circulating variants than current vaccines. This approach does not account for complex dynamics of how prior immunity skews recall responses to the updated vaccine. We: (i) use c...

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Detalles Bibliográficos
Autores principales: Desikan, Rajat, Linderman, Susanne L., Davis, Carl, Zarnitsyna, Veronika I., Ahmed, Hasan, Antia, Rustom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574365/
https://www.ncbi.nlm.nih.gov/pubmed/36263031
http://dx.doi.org/10.3389/fimmu.2022.985478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574365/
https://www.ncbi.nlm.nih.gov/pubmed/36263031
http://dx.doi.org/10.3389/fimmu.2022.985478

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