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The endoplasmic reticulum membrane protein Sec62 as potential therapeutic target in SEC62 overexpressing tumors
The human SEC62 gene is located on chromosome 3q, was characterized as a tumor driver gene and is found to be overexpressed in an ever-growing number of tumors, particularly those with 3q26 amplification. Where analyzed, SEC62 overexpression was associated with poor prognosis. Sec62 protein is a mem...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574383/ https://www.ncbi.nlm.nih.gov/pubmed/36262254 http://dx.doi.org/10.3389/fphys.2022.1014271 |