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The endoplasmic reticulum membrane protein Sec62 as potential therapeutic target in SEC62 overexpressing tumors

The human SEC62 gene is located on chromosome 3q, was characterized as a tumor driver gene and is found to be overexpressed in an ever-growing number of tumors, particularly those with 3q26 amplification. Where analyzed, SEC62 overexpression was associated with poor prognosis. Sec62 protein is a mem...

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Detalles Bibliográficos
Autores principales: Zimmermann, Julia S. M., Linxweiler, Johannes, Radosa, Julia C., Linxweiler, Maximilian, Zimmermann, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574383/
https://www.ncbi.nlm.nih.gov/pubmed/36262254
http://dx.doi.org/10.3389/fphys.2022.1014271