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Analyzing the mechanisms that facilitate the subtype-specific assembly of γ-aminobutyric acid type A receptors

Impaired inhibitory signaling underlies the pathophysiology of many neuropsychiatric and neurodevelopmental disorders including autism spectrum disorders and epilepsy. Neuronal inhibition is regulated by synaptic and extrasynaptic γ-aminobutyric acid type A receptors (GABA(A)Rs), which mediate phasi...

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Detalles Bibliográficos
Autores principales: Choi, Catherine, Smalley, Joshua L., Lemons, Abigail H. S., Ren, Qiu, Bope, Christopher E., Dengler, Jake S., Davies, Paul A., Moss, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574402/
https://www.ncbi.nlm.nih.gov/pubmed/36263376
http://dx.doi.org/10.3389/fnmol.2022.1017404