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A humanized mouse model for in vivo evaluation of invariant Natural Killer T cell responses

Invariant natural killer T (iNKT) cells mediate immune responses when stimulated by glycolipid agonists presented by CD1d. In extensive studies of synthetic analogues of α-galactosyl ceramides, we identified numerous examples of significant differences in the recognition of specific glycolipids in w...

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Detalles Bibliográficos
Autores principales: Saavedra-Avila, Noemi Alejandra, Dellabona, Paolo, Casorati, Giulia, Veerapen, Natacha, Besra, Gurdyal S., Howell, Amy R., Porcelli, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574442/
https://www.ncbi.nlm.nih.gov/pubmed/36263021
http://dx.doi.org/10.3389/fimmu.2022.1011209