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Single‐cell transcriptome profiling reveals the key role of ZNF683 in natural killer cell exhaustion in multiple myeloma

BACKGROUNDS: Decreased cytotoxicity of natural killer (NK) cells has been shown in multiple myeloma (MM). However, the underlying molecular mechanisms remain unclear. Here, by using single‐cell RNA sequencing analysis and in vitro experiments, we aim to uncover and validate molecularly distinctive i...

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Detalles Bibliográficos
Autores principales: Li, Xin, Chen, Mengping, Wan, Yike, Zhong, Lu, Han, Xiaofeng, Chen, Xiaotong, Xiao, Fei, Liu, Jia, Zhang, Yiwei, Zhu, Di, Xiang, Jing, Liu, Junling, Huang, Honghui, Hou, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574488/
https://www.ncbi.nlm.nih.gov/pubmed/36245253
http://dx.doi.org/10.1002/ctm2.1065