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Evaluating the Fragility of Long-Term Outcomes for Neoadjuvant versus Adjuvant Chemotherapy Prescription in Early Breast Cancer: Pooled Data from 10 Randomised Clinical Trials

INTRODUCTION: Randomised clinical trials (RCTs) report similar outcomes following neoadjuvant (NAC) and adjuvant chemotherapy (AC) in breast cancer. “Fragility Indices” (FI) test significance reversal reported in RCTs. AIM: To evaluate the FI of findings from RCTs assessing outcomes of NAC and AC. M...

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Detalles Bibliográficos
Autores principales: Davey, Matthew G, Kerin, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574564/
https://www.ncbi.nlm.nih.gov/pubmed/36262332
http://dx.doi.org/10.2147/BCTT.S379393