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Whole-exome sequencing of epithelial ovarian carcinomas differing in resistance to platinum therapy

Epithelial ovarian carcinoma (EOC) is highly fatal because of the risk of resistance to therapy and recurrence. We performed whole-exome sequencing of blood and tumor tissue pairs of 50 patients with surgically resected EOC. Compared with sensitive patients, platinum-resistant patients had a signifi...

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Detalles Bibliográficos
Autores principales: Hlaváč, Viktor, Holý, Petr, Václavíková, Radka, Rob, Lukáš, Hruda, Martin, Mrhalová, Marcela, Černaj, Petr, Bouda, Jiří, Souček, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574568/
https://www.ncbi.nlm.nih.gov/pubmed/36229065
http://dx.doi.org/10.26508/lsa.202201551