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Alternative mammalian strategies leading towards gastrulation: losing polar trophoblast (Rauber's layer) or gaining an epiblast cavity
Using embryological data from 14 mammalian orders, the hypothesis is presented that in placental mammals, epiblast cavitation and polar trophoblast loss are alternative developmental solutions to shield the central epiblast from extraembryonic signalling. It is argued that such reciprocal signalling...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Royal Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574635/ https://www.ncbi.nlm.nih.gov/pubmed/36252216 http://dx.doi.org/10.1098/rstb.2021.0254 |