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Chemical Toolkit for PARK7: Potent, Selective, and High-Throughput

[Image: see text] The multifunctional human Parkinson’s disease protein 7 (PARK7/DJ1) is an attractive therapeutic target due to its link with early-onset Parkinson’s disease, upregulation in various cancers, and contribution to chemoresistance. However, only a few compounds have been identified to...

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Detalles Bibliográficos
Autores principales: Jia, Yuqing, Kim, Robbert Q., Kooij, Raymond, Ovaa, Huib, Sapmaz, Aysegul, Geurink, Paul P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574860/
https://www.ncbi.nlm.nih.gov/pubmed/36149939
http://dx.doi.org/10.1021/acs.jmedchem.2c01113