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Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases

[Image: see text] In view of the worldwide antimicrobial resistance (AMR) threat, new bacterial targets and anti-infective agents are needed. Since important roles in bacterial pathogenesis have been demonstrated for the collagenase H and G (ColH and ColG) from Clostridium histolyticum, collagenase...

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Detalles Bibliográficos
Autores principales: Alhayek, Alaa, Abdelsamie, Ahmed S., Schönauer, Esther, Camberlein, Virgyl, Hutterer, Evelyn, Posselt, Gernot, Serwanja, Jamil, Blöchl, Constantin, Huber, Christian G., Haupenthal, Jörg, Brandstetter, Hans, Wessler, Silja, Hirsch, Anna K. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574867/
https://www.ncbi.nlm.nih.gov/pubmed/36154055
http://dx.doi.org/10.1021/acs.jmedchem.2c00785