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PD-1/PD-L1 combined with LAG3 is associated with clinical activity of immune checkpoint inhibitors in metastatic primary pulmonary lymphoepithelioma-like carcinoma

Primary pulmonary lymphoepithelioma-like carcinoma (PLELC) is an Epstein–Barr virus (EBV)-related, rare subtype of non-small-cell lung cancer (NSCLC). Immune checkpoint inhibitors (ICI) show durable responses in advanced NSCLC. However, their effects and predictive biomarkers in PLELC remain poorly...

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Detalles Bibliográficos
Autores principales: Zhong, Yu-Min, Yin, Kai, Chen, Yu, Xie, Zhi, Lv, Zhi-Yi, Yang, Jin-Ji, Yang, Xue-Ning, Zhou, Qing, Wang, Bin-Chao, Zhong, Wen-Zhao, Gao, Ling-Ling, Zhou, Wen-Bin, Chen, Ji, Tu, Hai-Yan, Liao, Ri-Qiang, Zhang, Dong-Kun, Zhang, Shui-Lian, Lu, Dan-Xia, Zheng, Hong-Bo, Zhang, Heng-Hui, Wu, Yi-Long, Zhang, Xu-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574915/
https://www.ncbi.nlm.nih.gov/pubmed/36263036
http://dx.doi.org/10.3389/fimmu.2022.951817