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Targeting the Phosphatidylserine-Immune Checkpoint with a Small-Molecule Maytansinoid Conjugate

[Image: see text] Ligand-targeting drug delivery systems have made significant strides for disease treatments with numerous clinical approvals in this era of precision medicine. Herein, we report a class of small molecule-based immune checkpoint-targeting maytansinoid conjugates. From the ligand tar...

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Detalles Bibliográficos
Autores principales: Lo, Chen-Fu, Chiu, Tai-Yu, Liu, Yu-Tzu, Pan, Pei-Yun, Liu, Kuan-Liang, Hsu, Chia-Yu, Fang, Ming-Yu, Huang, Yu-Chen, Yeh, Teng-Kuang, Hsu, Tsu-An, Chen, Chiung-Tong, Huang, Li-Rung, Tsou, Lun Kelvin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574934/
https://www.ncbi.nlm.nih.gov/pubmed/36153998
http://dx.doi.org/10.1021/acs.jmedchem.2c00631