Hypercholesterolemia promotes autoantibody production and a lupus‐like pathology via decreased DNase‐mediated clearance of DNA

Hypercholesterolemia exacerbates autoimmune response and accelerates the progression of several autoimmune disorders, but the mechanistic basis is not well understood. We recently demonstrated that hypercholesterolemia is associated with increased serum extracellular DNA levels secondary to a defect...

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Detalles Bibliográficos
Autores principales: Dhawan, Umesh Kumar, Margraf, Andreas, Lech, Maciej, Subramanian, Manikandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575094/
https://www.ncbi.nlm.nih.gov/pubmed/36098213
http://dx.doi.org/10.1111/jcmm.17556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575094/
https://www.ncbi.nlm.nih.gov/pubmed/36098213
http://dx.doi.org/10.1111/jcmm.17556

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