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Synthesis and evaluation of a novel analgesic conotoxin Lt7b that inhibits calcium currents and increases sodium currents
Conotoxins are promising neuropharmacological tools and drug candidates due to their high efficiency and specificity in targeting ion channels or neurotransmitter receptors. In this study, a novel O(2)‐superfamily conotoxin, Lt7b, was synthesized and its pharmacological functions were evaluated. Lt7...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575111/ https://www.ncbi.nlm.nih.gov/pubmed/36050866 http://dx.doi.org/10.1111/jcmm.17521 |