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Synthesis and evaluation of a novel analgesic conotoxin Lt7b that inhibits calcium currents and increases sodium currents

Conotoxins are promising neuropharmacological tools and drug candidates due to their high efficiency and specificity in targeting ion channels or neurotransmitter receptors. In this study, a novel O(2)‐superfamily conotoxin, Lt7b, was synthesized and its pharmacological functions were evaluated. Lt7...

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Detalles Bibliográficos
Autores principales: Wu, Yun, Yang, Manyi, Li, Yubin, Zhang, Wei, Zhou, Maojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575111/
https://www.ncbi.nlm.nih.gov/pubmed/36050866
http://dx.doi.org/10.1111/jcmm.17521