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Delta‐like ligand‐4 regulates Notch‐mediated maturation of second heart field progenitor‐derived pharyngeal arterial endothelial cells

Mesodermal progenitors in the second heart field (SHF) express Delta‐like‐ligand 4 (Dll4) that regulates Notch‐mediated proliferation. As cells of SHF lineage mature to assume endocardial and myocardial cell fates, we have shown that Dll4 expression is lost, and the subsequent expression of another...

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Detalles Bibliográficos
Autores principales: De Zoysa, Prashan, Toubat, Omar, Harvey, Drayton C., Yi, Christopher, Liu, Jiang, Cavallero, Susana, Hong, Young‐Kwon, Sucov, Henry M., Kumar, Subramanyan Ram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575135/
https://www.ncbi.nlm.nih.gov/pubmed/36082581
http://dx.doi.org/10.1111/jcmm.17542