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MEPP: more transparent motif enrichment by profiling positional correlations

Score-based motif enrichment analysis (MEA) is typically applied to regulatory DNA to infer transcription factors (TFs) that may modulate transcription and chromatin state in different conditions. Most MEA methods determine motif enrichment independent of motif position within a sequence, even when...

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Detalles Bibliográficos
Autores principales: Delos Santos, Nathaniel P, Duttke, Sascha, Heinz, Sven, Benner, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575187/
https://www.ncbi.nlm.nih.gov/pubmed/36267125
http://dx.doi.org/10.1093/nargab/lqac075