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Evolutionary dynamics of pseudoautosomal region 1 in humans and great apes

BACKGROUND: The pseudoautosomal region 1 (PAR1) is a 2.7 Mb telomeric region of human sex chromosomes. PAR1 has a crucial role in ensuring proper segregation of sex chromosomes during male meiosis, exposing it to extreme recombination and mutation processes. We investigate PAR1 evolution using popul...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Bergman, Juraj, Schierup, Mikkel Heide
Format: Online Artikel Text
Sprache:English
Veröffentlicht: BioMed Central 2022
Schlagworte:
Online Zugang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575207/
https://www.ncbi.nlm.nih.gov/pubmed/36253794
http://dx.doi.org/10.1186/s13059-022-02784-x