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Evolutionary dynamics of pseudoautosomal region 1 in humans and great apes
BACKGROUND: The pseudoautosomal region 1 (PAR1) is a 2.7 Mb telomeric region of human sex chromosomes. PAR1 has a crucial role in ensuring proper segregation of sex chromosomes during male meiosis, exposing it to extreme recombination and mutation processes. We investigate PAR1 evolution using popul...
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Format: | Online Artikel Text |
Sprache: | English |
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BioMed Central
2022
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Online Zugang: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575207/ https://www.ncbi.nlm.nih.gov/pubmed/36253794 http://dx.doi.org/10.1186/s13059-022-02784-x |