Cationic amino acid transporter-1 (CAT-1) promotes fibroblast-like synoviocyte proliferation and cytokine secretion by taking up L-arginine in rheumatoid arthritis

BACKGROUND: Abnormal proliferation of fibroblast-like synoviocytes (FLSs) in the synovial lining layer is the primary cause of synovial hyperplasia and joint destruction in rheumatoid arthritis (RA). Currently, the relationship between metabolic abnormalities and FLS proliferation is a new focus of...

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Detalles Bibliográficos
Autores principales: Lu, Ying, Hao, Chongbo, Yu, Shanshan, Ma, Zuan, Fu, Xuelian, Qin, Mingqing, Ding, Menglei, Xu, Zengguang, Fan, Lieying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575222/
https://www.ncbi.nlm.nih.gov/pubmed/36253807
http://dx.doi.org/10.1186/s13075-022-02921-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575222/
https://www.ncbi.nlm.nih.gov/pubmed/36253807
http://dx.doi.org/10.1186/s13075-022-02921-8

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