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Blood transcriptomics to facilitate diagnosis and stratification in pediatric rheumatic diseases – a proof of concept study

BACKGROUND: Transcriptome profiling of blood cells is an efficient tool to study the gene expression signatures of rheumatic diseases. This study aims to improve the early diagnosis of pediatric rheumatic diseases by investigating patients’ blood gene expression and applying machine learning on the...

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Detalles Bibliográficos
Autores principales: Ha, My Kieu, Bartholomeus, Esther, Van Os, Luc, Dandelooy, Julie, Leysen, Julie, Aerts, Olivier, Siozopoulou, Vasiliki, De Smet, Eline, Gielen, Jan, Guerti, Khadija, De Maeseneer, Michel, Herregods, Nele, Lechkar, Bouchra, Wittoek, Ruth, Geens, Elke, Claes, Laura, Zaqout, Mahmoud, Dewals, Wendy, Lemay, Annelies, Tuerlinckx, David, Weynants, David, Vanlede, Koen, van Berlaer, Gerlant, Raes, Marc, Verhelst, Helene, Boiy, Tine, Van Damme, Pierre, Jansen, Anna C., Meuwissen, Marije, Sabato, Vito, Van Camp, Guy, Suls, Arvid, Werff ten Bosch, Jutte Van der, Dehoorne, Joke, Joos, Rik, Laukens, Kris, Meysman, Pieter, Ogunjimi, Benson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575227/
https://www.ncbi.nlm.nih.gov/pubmed/36253751
http://dx.doi.org/10.1186/s12969-022-00747-x