Global early replication disrupts gene expression and chromatin conformation in a single cell cycle

BACKGROUND: The early embryonic divisions of many organisms, including fish, flies, and frogs, are characterized by a very rapid S-phase caused by high rates of replication initiation. In somatic cells, S-phase is much longer due to both a reduction in the total number of initiation events and the i...

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Detalles Bibliográficos
Autores principales: Santos, Miguel M., Johnson, Mark C., Fiedler, Lukáš, Zegerman, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575230/
https://www.ncbi.nlm.nih.gov/pubmed/36253803
http://dx.doi.org/10.1186/s13059-022-02788-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575230/
https://www.ncbi.nlm.nih.gov/pubmed/36253803
http://dx.doi.org/10.1186/s13059-022-02788-7

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