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Normalization and de-noising of single-cell Hi-C data with BandNorm and scVI-3D
Single-cell high-throughput chromatin conformation capture methodologies (scHi-C) enable profiling of long-range genomic interactions. However, data from these technologies are prone to technical noise and biases that hinder downstream analysis. We develop a normalization approach, BandNorm, and a d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575231/ https://www.ncbi.nlm.nih.gov/pubmed/36253828 http://dx.doi.org/10.1186/s13059-022-02774-z |