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The single cell transcriptional landscape of esophageal adenocarcinoma and its modulation by neoadjuvant chemotherapy

Immune checkpoint blockade has recently proven effective in subsets of patients with esophageal adenocarcinoma (EAC) but little is known regarding the EAC immune microenvironment. We determined the single cell transcriptional profile of EAC in 8 patients who were treatment-naive (n = 4) or had recei...

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Detalles Bibliográficos
Autores principales: Croft, Wayne, Evans, Richard P. T., Pearce, Hayden, Elshafie, Mona, Griffiths, Ewen A., Moss, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575245/
https://www.ncbi.nlm.nih.gov/pubmed/36253784
http://dx.doi.org/10.1186/s12943-022-01666-x