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The single cell transcriptional landscape of esophageal adenocarcinoma and its modulation by neoadjuvant chemotherapy
Immune checkpoint blockade has recently proven effective in subsets of patients with esophageal adenocarcinoma (EAC) but little is known regarding the EAC immune microenvironment. We determined the single cell transcriptional profile of EAC in 8 patients who were treatment-naive (n = 4) or had recei...
Autores principales: | Croft, Wayne, Evans, Richard P. T., Pearce, Hayden, Elshafie, Mona, Griffiths, Ewen A., Moss, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575245/ https://www.ncbi.nlm.nih.gov/pubmed/36253784 http://dx.doi.org/10.1186/s12943-022-01666-x |
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