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Untargeted metabolomics analysis reveals Mycobacterium tuberculosis strain H37Rv specifically induces tryptophan metabolism in human macrophages

BACKGROUND: Tuberculosis (TB) caused by Mycobacterium tuberculosis (M. tb) remains a global health issue. The characterized virulent M. tb H37Rv, avirulent M. tb H37Ra and BCG strains are widely used as reference strains to investigate the mechanism of TB pathogenicity. Here, we attempted to determi...

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Detalles Bibliográficos
Autores principales: Xiao, Guohui, Zhang, Su, Zhang, Like, Liu, Shuyan, Li, Guobao, Ou, Min, Zeng, Xuan, Wang, Zhaoqin, Zhang, Guoliang, Lu, Shuihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575276/
https://www.ncbi.nlm.nih.gov/pubmed/36253713
http://dx.doi.org/10.1186/s12866-022-02659-y