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Caveolin-1 accelerates hypoxia-induced endothelial dysfunction in high-altitude cerebral edema

BACKGROUND: High-altitude cerebral edema (HACE) is a serious and potentially fatal brain injury that is caused by acute hypobaric hypoxia (HH) exposure. Vasogenic edema is the main pathological factor of this condition. Hypoxia-induced disruptions of tight junctions in the endothelium trigger blood‒...

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Detalles Bibliográficos
Autores principales: Xue, Yan, Wang, Xueting, Wan, Baolan, Wang, Dongzhi, Li, Meiqi, Cheng, Kang, Luo, Qianqian, Wang, Dan, Lu, Yapeng, Zhu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575296/
https://www.ncbi.nlm.nih.gov/pubmed/36253854
http://dx.doi.org/10.1186/s12964-022-00976-3