Synaptic dysfunction in ALS and FTD: anatomical and molecular changes provide insights into mechanisms of disease

Synaptic loss is a pathological feature of all neurodegenerative diseases including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). ALS is a disease of the cortical and spinal motor neurons resulting in fatal paralysis due to denervation of muscles. FTD is a form of dementia t...

Descripción completa

Detalles Bibliográficos
Autores principales: Gelon, Pauline A., Dutchak, Paul A., Sephton, Chantelle F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575515/
https://www.ncbi.nlm.nih.gov/pubmed/36263379
http://dx.doi.org/10.3389/fnmol.2022.1000183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575515/
https://www.ncbi.nlm.nih.gov/pubmed/36263379
http://dx.doi.org/10.3389/fnmol.2022.1000183

Ejemplares similares