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Synaptic dysfunction in ALS and FTD: anatomical and molecular changes provide insights into mechanisms of disease

Synaptic loss is a pathological feature of all neurodegenerative diseases including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). ALS is a disease of the cortical and spinal motor neurons resulting in fatal paralysis due to denervation of muscles. FTD is a form of dementia t...

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Detalles Bibliográficos
Autores principales:	Gelon, Pauline A., Dutchak, Paul A., Sephton, Chantelle F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575515/ https://www.ncbi.nlm.nih.gov/pubmed/36263379 http://dx.doi.org/10.3389/fnmol.2022.1000183

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