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Precise quantitative evaluation of pharmacokinetics of cisplatin using a radio-platinum tracer in tumor-bearing mice

The platinum-based antineoplastic drug cisplatin is commonly used for chemotherapy in clinics. This work aims to demonstrate a radio-platinum tracer is useful for precisely quantifying small amounts of platinum in pharmacokinetics studies. METHODS: A cisplatin radiotracer (radio-cisplatin) was synth...

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Detalles Bibliográficos
Autores principales: Obata, Honoka, Tsuji, Atsushi B., Sudo, Hitomi, Sugyo, Aya, Minegishi, Katsuyuki, Nagatsu, Kotaro, Ogawa, Mikako, Zhang, Ming-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575570/
https://www.ncbi.nlm.nih.gov/pubmed/36120823
http://dx.doi.org/10.1097/MNM.0000000000001614