Easy access to α-ketoamides as SARS-CoV-2 and MERS M(pro) inhibitors via the PADAM oxidation route

SARS-CoV-2 caused worldwide the current outbreak called COVID-19. Despite multiple countermeasures implemented, there is an urgent global need for new potent and efficient antiviral drugs against this pathogen. In this context, the main protease (M(pro)) of SARS-CoV-2 is an essential viral enzyme an...

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Detalles Bibliográficos
Autores principales: Pelliccia, Sveva, Cerchia, Carmen, Esposito, Francesca, Cannalire, Rolando, Corona, Angela, Costanzi, Elisa, Kuzikov, Maria, Gribbon, Philip, Zaliani, Andrea, Brindisi, Margherita, Storici, Paola, Tramontano, Enzo, Summa, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575579/
https://www.ncbi.nlm.nih.gov/pubmed/36332546
http://dx.doi.org/10.1016/j.ejmech.2022.114853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575579/
https://www.ncbi.nlm.nih.gov/pubmed/36332546
http://dx.doi.org/10.1016/j.ejmech.2022.114853

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