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Advanced Glycation End-Product Precursor Methylglyoxal May Lead to Development of Alzheimer’s Disease

INTRODUCTION: Diabetes mellitus (DM) is characterized by chronic hyperglycemia and diabetic complications. Exacerbated cortical neuronal degeneration was observed in Alzheimer’s disease (AD) patients with DM. In fact, DM is now considered a risk factor of AD, as DM-induced activation of stress respo...

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Detalles Bibliográficos
Autores principales: Li, Wai Yin, Lee, Cheuk Yan, Lee, Kwan Ming, Zhang, Ge, Lyu, Aiping, Yue, Kevin Kin Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575592/
https://www.ncbi.nlm.nih.gov/pubmed/36262805
http://dx.doi.org/10.2147/DMSO.S382927