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A protein synthesis brake for hematopoietic stem cell maintenance
Bmi1 is essential for normal and leukemic hematopoiesis, but its target genes in hematopoietic stem cells (HSCs) are incompletely understood. In this issue of Genes & Development, Burgess et al. (pp. 887–900) demonstrate a novel role of Bmi1 in regulating ribosome biogenesis and protein synthesi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575693/ https://www.ncbi.nlm.nih.gov/pubmed/36207141 http://dx.doi.org/10.1101/gad.350107.122 |