Data-independent acquisition-based quantitative proteomic analysis of m.3243A>G MELAS reveals novel potential pathogenesis and therapeutic targets

The pathogenesis of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke like episodes (MELAS) syndrome has not been fully elucidated. The m.3243A > G mutation which is responsible for 80% MELAS patients affects proteins with undetermined functions. Therefore, we performed quantitat...

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Detalles Bibliográficos
Autores principales: Chang, Xueli, Yin, Zhaoxu, Zhang, Wei, Shi, Jiaying, Pu, Chuanqiang, Shi, Qiang, Wang, Juan, Zhang, Jing, Yan, Li, Yang, Wenqu, Guo, Junhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
5300
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575705/
https://www.ncbi.nlm.nih.gov/pubmed/36254078
http://dx.doi.org/10.1097/MD.0000000000030938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575705/
https://www.ncbi.nlm.nih.gov/pubmed/36254078
http://dx.doi.org/10.1097/MD.0000000000030938

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