Frontotemporal degeneration genetic risk loci and transcription regulation as a possible mechanistic link to disease risk

The etiology of Frontotemporal Degeneration (FTD) is not well understood. Genetic studies have established common genetic variants (GVs) that are associated with increased FTD risk. We review previous genome wide association studies (GWAS) of FTD and nominate specific transcriptional regulators as p...

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Detalles Bibliográficos
Autores principales: Sawyer, Russell P., Stone, Hillarey K., Salim, Hanan, Lu, Xiaoming, Weirauch, Matthew T., Kottyan, Leah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575772/
https://www.ncbi.nlm.nih.gov/pubmed/36253972
http://dx.doi.org/10.1097/MD.0000000000031078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575772/
https://www.ncbi.nlm.nih.gov/pubmed/36253972
http://dx.doi.org/10.1097/MD.0000000000031078

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