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Identification of suitable reference genes for normalization of reverse transcription quantitative real-time PCR (RT-qPCR) in the fibrotic phase of the bleomycin mouse model of pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a severe lung disease with a poor prognosis and few treatment options. In the most widely used experimental model for this disease, bleomycin is administered into the lungs of mice, causing a reaction of inflammation and consequent fibrosis that resembles the p...

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Detalles Bibliográficos
Autores principales: Norman, Oula, Koivunen, Jarkko, Mäki, Joni M., Pihlajaniemi, Taina, Heikkinen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576074/
https://www.ncbi.nlm.nih.gov/pubmed/36251700
http://dx.doi.org/10.1371/journal.pone.0276215